Articles Tagged With:
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COVID-19 Vaccine mRNA Suspension for Injection (Comirnaty, Spikevax)
The Food and Drug Administration has approved and granted emergency use authorization for updated messenger ribonucleic acid (mRNA) COVID-19 vaccines.
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Are Mineralocorticoid Receptor Antagonists Safe in Heart Failure Patients with Renal Dysfunction?
A post hoc analysis of the RALES and EMPHASIS HF trials has shown that, although treatment of heart failure with reduced left ventricular ejection fraction in patients with mineralocorticoid receptor antagonists can cause a significant deterioration in renal function, the benefits outweigh the adverse effects and should not lead to automatic therapy discontinuation.
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Out of Africa Again? A New Version of Mpox
A novel mpox clade has emerged in Africa and has the potential for a global epidemic.
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Thrombectomy for Basilar Artery Occlusion
This randomized trial from China demonstrates a dramatic benefit from endovascular thrombectomy in patients with acute basilar artery occlusion. This benefit was sustained and improved at one year compared to 90 days.
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Clinicopathological Correlation in Motor Neuron Disease and Frontotemporal Degeneration
Frontotemporal lobar degeneration commonly occurs with motor neuron disease and has similar cytoplasmic neuronal aggregates of TAR deoxyribonucleic acid-binding protein 43 (TDP-43) in the brain as well as the spinal cord.
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The Clinical Spectrum of Anti-GQ1b Antibody Syndrome
Antibodies targeting gangliosides, glycosphingolipids that play a role in synaptic plasticity, neurotransmission derangements, and axonal growth all are implicated in many autoimmune peripheral neuropathies. Miller Fisher syndrome (MFS) is the clinical triad of external ophthalmoplegia, ataxia, and areflexia classically associated with anti-GQ1b. However, there are other subtypes that present with only one or two clinical features of the clinical triad.
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Stratifying Seizure Risk with a Rapid EEG
In a retrospective, large, multicenter trial, rapid response electroencephalogram (EEG) was found to be non-inferior to conventional EEG when incorporated into the 2HELPS2B score to guide how long patients should stay on EEG.
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Blood Biomarkers for the Diagnosis of Alzheimer’s Disease
In this population-based study of patients in Sweden with cognitive complaints, mild cognitive impairment, and dementia, the use of blood biomarkers, specifically, phosphorylated tau 217 and amyloid-beta 42/40 ratios, improved the diagnostic accuracy for pathological Alzheimer’s disease in primary care patients as well as patients seen by dementia specialists.
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The Fourth Trimester: Emergencies in the Postpartum Period
The most common causes of maternal death in the postpartum period include infection, hemorrhage, cardiomyopathy, and mental health-related conditions.
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Infectious Disease Updates
Managing Neurosyphilis; Combatting the Resurgence of Syphilis